Title of article :
Mild, Efficient and Highly Selective Hydrolysis of Acetonides with Antimony Trichloride
Author/Authors :
Wu, Qinpei Beijing Institute of Technology - Dept of Appl Chem, China , Chen, Wei Beijing Institute of Technology - School of Life Science and Technology, China , Wang, Yuan Beijing Institute of Technology - School of Life Science and Technology, Beijing , Qu, Yunbo Beijing Institute of Technology - School of Life Science and Technology, China , Zhang, Qingshan Beijing Institute of Technology - Dept of Appl Chem, China
Abstract :
A mild and efficient procedure for chemoselective and regioselective hydrolysis of acetonide with SbCl3 in the presence of other frequently used hydroxy protecting groups, TBDMS, TBDPS, Bz, Bn, Ac, Ts andTr, was described. The mechanism was examined and proposed.
Keywords :
Hydrolysis , acetonide , antimony , protecting groups , catalysis , lewis acid
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
