Title of article :
Stereoselective Synthesis of C3-C10 and C13-C21 Fragments of Laulimalide#
Author/Authors :
Punna, Sreenivas Discovery Laboratory - Organic Chemistry Division III, India , Rakesh Discovery Laboratory - Organic Chemistry Division III, India , Prabhakar, Anabathula Indian Institute of ChemicalTechnology - NMR Centre, India , Sharmaa, Gangavaram V.M. Organic Chemistry Division III - Discovery Laboratory, India , Kunwar, Ajit Chand Indian Institute of Chemical Technology - NMR Centre, India
Abstract :
Synthesis of the C3-C10 and C13-C21 segments, having seven asymmetric centers of the marinemacrolide, (-)-laulimalide is reported. The requisite stereogenic centers were generated on the chirons by the application of asymmetric reactions.
Keywords :
Marine macrolide , laulimalide , Sharpless asymmetric epoxidation , stereoselective synthesis , chiron , intramolecular cyclization.
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
