Author/Authors :
Gopalakrishnan, Mannathusamy Annamalai University - Department of Chemistry, India , Sureshkumar, Purushothaman Annamalai University - Department of Chemistry, India , Kanagarajan, Vijayakumar Annamalai University - Department of Chemistry, India , Thanusu, Jeyaraman Annamalai University - Department of Chemistry, India , Govindaraju, Ramalingam Annamalai University - Department of Chemistry, India , Ezhilarasi, Muthuvel R. Annamalai University - Department of Chemistry, India
Abstract :
Sulfated zirconia (ZrO2/SO42-) solid superacid has been proved to be an efficient reusableheterogeneous catalyst for three-component one-pot cyclocondensation reaction of ß-dicarbonyl compounds and urea/thiourea with structurally diverse aromatic aldehydes in solvent-free conditions to furnish the corresponding 3,4-dihydropyrimidin-2(1H)-ones and -thiones in good to excellent yields both under microwave irradiation and thermal conditions.
Keywords :
Biginelli reaction , sulfated zirconia , dihydropyrimidinones , microwave irradiation , green chemistry
