Author/Authors :
Sharma, Anubha Bhabha Atomic Research Centre - Bio-Organic Division, India , Roy, Siddharth Bhabha Atomic Research Centre - Bio-Organic Division, India , Goswami, Dibakar Bhabha Atomic Research Centre - Bio-Organic Division, India , Chattopadhyay, Angshuman Bhabha Atomic Research Centre - Bio-Organic Division, India , Chattopadhyay, Subrata Bhabha Atomic Research Centre - Bio-Organic Division, India
Abstract :
A facile synthesis of the title compound has been developed starting from the crotylated product of(R)-cyclohexylideneglyceraldehyde (2). The key features of the synthesis were stereochemical control of the crotylation by alteration of reaction conditions, operational simplicity and the use of inexpensive compounds/reagents.
Keywords :
Asymmetric synthesis , (R) , cyclohexylideneglyceraldehyde , hapalosin , b , hydroxy acid
