Title of article
An Asymmetric Synthesis of the β-Hydroxy Acid Segment of Hapalosin
Author/Authors
Sharma, Anubha Bhabha Atomic Research Centre - Bio-Organic Division, India , Roy, Siddharth Bhabha Atomic Research Centre - Bio-Organic Division, India , Goswami, Dibakar Bhabha Atomic Research Centre - Bio-Organic Division, India , Chattopadhyay, Angshuman Bhabha Atomic Research Centre - Bio-Organic Division, India , Chattopadhyay, Subrata Bhabha Atomic Research Centre - Bio-Organic Division, India
From page
741
To page
743
Abstract
A facile synthesis of the title compound has been developed starting from the crotylated product of(R)-cyclohexylideneglyceraldehyde (2). The key features of the synthesis were stereochemical control of the crotylation by alteration of reaction conditions, operational simplicity and the use of inexpensive compounds/reagents.
Keywords
Asymmetric synthesis , (R) , cyclohexylideneglyceraldehyde , hapalosin , b , hydroxy acid
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2718081
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