Title of article :
S,S-Dimethyl Dithiocarbonate as a Valuable Starting Material for the Synthesis of 5-Substituted Oxazolidinones Under Solid-Liquid Phase Transfer Catalysis (SL-PTC) Conditions
Author/Authors :
Landini, Dario Dipartimento di Chimica Organica e Industriale dell’Università, Italy , Salsa, Matteo Dipartimento di Chimica Organica e Industriale dell’Università, Italy , Carvoli, Gianni Dipartimento di Chimica Organica e Industriale dell’Università, Italy , Pecnikaj, Ilir Oxon Italia S.p.A, Italy
Abstract :
N-Alkyl and N-aryl 5-substituted oxazolidinones 12-19 were prepared in good to excellent yields by reaction ofN-alkyl and N-aryl 1,2-amino alcohols 3-10 with S,S-dimethyldithiocarbonate (11) in the presence of solid NaOH underSL-PTC conditions. The procedure is particularly suitable for scale-up the process involving the use of cheap and ecosafere agents under mild reaction conditions.
Keywords :
S , S , dimethyldithiocarbonate , 1 , 2 , amino alcohols , 5 , substituted oxazolidinones , phase , transfer catalysis , carbonylation reaction
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
