Author/Authors :
Saber, R. tehran university of medical sciences tums - Research Center for Science and Technology In Medicine (RCSTIM) - Nanotechnology Group, تهران, ايران , Sarkar, S. tehran university of medical sciences tums - Research Center for Science and Technology In Medicine (RCSTIM) - Nanotechnology Group, تهران, ايران , Gill, P. tehran university of medical sciences tums - Research Center for Science and Technology In Medicine (RCSTIM) - Nanotechnology Group, تهران, ايران , Gill, P. golestan university of medical sciences - Faculty of Advanced Medical Technologies - Department of Medical Nanotechnology (Nanomedicine), ايران , Nazari, B. isfahan university of technology - Department of Electrical and Computer Engineering, اصفهان, ايران , Faridani, F. tehran university of medical sciences tums - Research Center for Science and Technology In Medicine (RCSTIM) - Nanotechnology Group, تهران, ايران
Abstract :
A scanning tunneling microscope is a powerful tool for obtaining micrographs from conductive and semiconductive materials. The imaging technique has recently been improved for microscopy of nanostructured biomaterials on highly ordered atomic surfaces. We describe, here, high resolution imaging of individual IgM and IgG using a scanning tunneling microscope (Nama-STM) in air condition. The biomolecules were immobilized on the surface of Highly Ordered Pyrolytic Graphite (HOPG). Obtained micrographs could reveal structural details of immunoglobulins G and M on the atomically flat surfaces, Obtained results confirmed that STM could be more useful than other microscopy techniques for the analysis of single biomolecules.
Keywords :
SIM , IgG , IgM , Air condition , Nanostructured biomaterials.
