CASTLEMAN’S DISEASE: A CLINICOPATHOLOGICAL STUDY IN A TERTIARY CARE HOSPITAL, LAHORE

Castleman’s Disease is a rare, localized or generalized lymphoproliferative disorder of unknown etiology and varying clinical manifestations with a frequent mediastinal location but can be found in any other nodal or extranodal site. We report 4 patients with Castleman’s Disease diagnosed over a 2 year period (June 2011 to July 2013) at KEMU / Mayo Hospital, Lahore. The age, history, clinical presentation, laboratory investigations, radiological findings, gross and microscopic features of the lesions are presented indicating the heterogenous nature of this unique form of lymphoid hyperplasia.