ASSOCIATION OF SERUM URIC ACID WITH LEVEL OF BLOOD PRESSURE IN TYPE 2 DIABETIC PATIENTS

Background and Objectives: Diabetes mellitus (DM) is a chronic disease characterized by insulin deficiency or peripheral resistance resulting in hyperglycemia. Hyperuricemia has been reported with incre-ased risk of renal insufficiency. The objective of the study was to determine the association of uric acid with blood pressure in type 2 diabetic patients. Methods: In this study eighty patients with type 2 diabetes mellitus were included. No patient had his-tory of gout or history of using antihypertensive or uric acid lowering drugs. HbA1c was performed on Hemoglobin – Testing System (D-10-Biored Laboratories). Serum uric acid (UA), serum creatinine and plasma glucose were measured on fully automated chemistry analyzer (Metrolab – 2300). Results: The study population consisted of 80 subjects, among them 32 (40%) were male and 48 (60%) were female. Among 80 subjects, the age limit started from 50 years to 68 years with mean of 58.16 ±. Mean HbA1c level was 7.63 ± 1.6, mean uric acid level 5.86 ± 0.97 and mean creatinine level was 0.86 ± 0.20. Mean systolic and diastolic blood pressure were 124 ± 11.78 and 82.50 ± 8.49 respectively. Uric acid levels are correlated with blood pressure (systolic and diastolic) in diabetic patients.Conclusion: The present study demonstrated a strong correlation between serum uric acid and systolic and diastolic blood pressure levels in type 2 diabetic patients.