Four-Component Synthesis of Polyhydroquinolines via Unsymmetrical Hantzsch Reaction Employing Cu-IRMOF-3 as a Robust Heterogeneous Catalyst

In this report, an IRMOF3 was synthesized via a solvothermal method and then used as support for stabilizing Cu(II) ions. Characterization methods such as FTIR, XRD, SEM, and BET were employed to analyze produced Cu@IRMOF3, demonstrating that the suggested catalyst effectively conserved its structure throughout the synthesis processes. The FTIR results indicate that the presence of the NH2 group in the structure of the MOF helped stabilize the Cu(II) ions. The manufactured catalyst was used to prepare polyhydroquinoline derivatives which showed superior results.