Author/Authors :
Porozan, Samaneh Department of Emergency Medicine - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Alavinejad, Pezhman Alimentary Tract Research Center - Imam Khomeini Hospital Clinical Research Development Unit - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Mozafari, Javad Department of Emergency Medicine - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Kazem Mousavi, Hosein Department of Emergency Medicine - Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran , Delirrooyfard, Ali Imam Khomeini Hospital Clinical Research Development Unit - Ahvaz Jundis- hapur University of Medical Sciences, Ahvaz, Iran
Abstract :
BACKGROUND
Acute pancreatitis (AP) is a common cause of hospital admissions. Diagnosing AP in
patients presenting to emergency departments remains a challenge for physicians. Thus,
we aimed to evaluate the diagnostic accuracy of galectin-3 to find a new and effective
method for detecting AP.
METHODS
In this prospective cross-sectional study, 43 patients with a manifestation of AP were en-
rolled. The serum levels of galectin-3 were measured at admission and 48 hours later and
compared between the groups of patients with and without AP.
RESULTS
Serum levels of galectin-3 at admission and after 48 hours were significantly higher in
AP cases compared with non-AP individuals. The area under the curve (AUC) for galec-
tin-3 was 73.1%, which revealed a good accuracy in predicting the AP diagnosis.
CONCLUSION
Serum levels of galectin-3 at admission and after 48 hours were significantly higher in
AP cases, and their diagnostic value was acceptable in the detection of AP.
