Title of article :
Rescue potency of Eucalyptus oil against gamma-rays induced gastric ulceration
Author/Authors :
Tawfik, S Health Radiation Research Department - National Centre for Radiation Research and Technology (NCRRT) - Egyptian Atomic Energy Authority - P.O. Box: 29 - Nasr City, Cairo, Egypt , Elkady, A Health Radiation Research Department - National Centre for Radiation Research and Technology (NCRRT) - Egyptian Atomic Energy Authority - P.O. Box: 29 - Nasr City, Cairo, Egypt , Salama, S Radiation Biology Department - National Centre for Radiation Research and Technology (NCRRT) - Egyptian Atomic Energy Authority - P.O. Box: 29 - Nasr City, Cairo, Egypt
Abstract :
Background: Eucalyptus oil often used for medicinal purposes. Aims: The Eucalyptus oil gastro protective impact investigated against gamma-rays-exposure-induced gastric
ulceration in rats. Materials and Methods: Thirty-two rats were divided equally into
4groups; control, Eucalyptus oil (100mg/ kg), gamma-rays (7Gy) and Eucalyptus oil plus
gamma-rays treated groups. The stomach histopathology samples were examined. The
levels of malondialdehyde, reduced glutathione, superoxide dismutase, tumour
necrosis factor-α and the interleukin-1β were assessed. Results: The stomach
histopathological examination revealed that pre-treatment with Eucalyptus oil
enhanced regeneration of mucosal crypt cells. The results revealed a decreased level of
stomach malondialdehyde, inflammatory markers, increased levels of stomach
antioxidants markers in Eucalyptus oil plus gamma-rays treated group. Conclusion:
Eucalyptus oil ameliorates gamma-rays-induced gastric ulceration that could attribute to its antioxidant, anti-apoptotic and radioprotective activities.
Keywords :
Eucalyptus oil , gastriculceration , gamma - rays , rats , radioprotector
Journal title :
International Journal of Radiation Research
