Author/Authors :
Singh, Garima Department of Bioinformatics - School of Interdisciplinary Sciences, Jamia Hamdard, New Delhi, India , Janardhanan, Akhil Department of Computational Biology and Bioinformatics - University of Kerala, Trivandrum, Kerela, India , Sharma,Shweta Department of Biochemistry - School of Chemical and Biological Sciences, Jamia Hamdard, New Delhi, India , Vyas, Bharti Department of Bioinformatics - School of Interdisciplinary Sciences, Jamia Hamdard, New Delhi, India , Ali, Shakir Department of Biochemistry - School of Chemical and Biological Sciences, Jamia Hamdard, New Delhi, India , Akhter, Mymoona Department of Pharmaceutical Chemistry - School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India
Abstract :
Objectives: This study aims to analyze epidemiological data that diabetes leads to increased
susceptibility to initial tuberculosis infection or if diabetes leads to increased progression from latent
tuberculosis to active tuberculosis.
Methods: A simplified MEDLINE search method has been used in this study. The PubMed’s Clinical
Queries, which have "research methodology filters" to study the patterns, causes, and clinical effects of
health and the disease conditions in defined populations, were explored and extracted.
Results: Using the keyword-based queries in PubMed/ Medline and Embase, 38 relevant published
studies were collected from 1970 to 2020. Published studies from the literature search were combined
with the observational studies of summary statistics which can further be used for clinical trials.
Conclusion: The high prevalence of diabetes is a factor that increases the incidence of tuberculosis
and is considered in the fight against tuberculosis worldwide. There have been many significant recent
advances in knowledge regarding diabetes-associated tuberculosis's epidemiology, management, and
control. J Microbiol Infect Dis 2021; 11(4):191-200.
Keywords :
Mycobacterium tuberculosis , Diabetes , Epidemiology , Review analysis
