Title of article :
Medical system error causing methotrexate poisoning and delay in diagnosis: report of two cases
Author/Authors :
Reihani, Hamidreza Department of Emergency Medicine - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Ziadi Lotfabadi, Maryam Department of Emergency Medicine - Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
Objective: We are going to alert the emergency physicians to be aware of drugs side
effects. Some drugs like methotrexate are not routine drugs, and the symptoms may be
miss diagnosed if not completely notified.
Case Presentation: We present two patients under treatment with methotrexate. Both of
them suffered from methotrexate poisoning due to improper use. We discuss the causes of
methotrexate poisoning and its prevention.
Conclusion: A significant proportion of methotrexate users may not be completely aware
of its proper use and the side effects. One of the important ways to prevent the toxicity of
methotrexate is educating patients and their companions in order to use it correctly.
Keywords :
Methotrexate toxicity , Mucocutaneous lesions , Pancytopenia
Journal title :
Journal of Emergency Practice and Trauma
