Author/Authors :
Eslamian, Ladan Dental Research Center - Research Institute of Dental Sciences - School of Dentistry - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Ebadifar, Aliasghar Dentofacial Deformities Research Center - Research Institute of Dental Sciences, School of Dentistry - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mohebbi Rad, Masoud not Affiliation , Motamedian, Reza Department of Orthodontics - School of Dentistry - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Badiee, Mohammad Reza Department of Orthodontics - School of Dentistry - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mohammad-Rahimi, Hossein Dental Research Center - Research Institute of Dental Sciences - School of Dentistry - Shahid Beheshti University of Medical Sciences, Tehran, Iran , farahani, Mohammadhossein Dental Research Center -Research Institute of Dental Sciences - School of Dentistry - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
ntroduction: This study was performed to compare the effects of single and multiple irradiations of
low-level laser therapy (LLLT) on bone regeneration in a mid-palatal suture following rapid palatal
expansion (RPE).
Methods: In this animal study, 40 male Wistar rats underwent RPE for 7 days and were divided into 4
groups including A: single LLLT on day 7, B: Multiple LLLT on days 7, 9, 11, 13 and 15, C: control (no
LLLT), and D: sacrificed on day 7. Animals in group D were used to determine the amount of suture
expansion. LLLT was done by a diode laser set at an 808 nm wavelength with a useful power output
of 100 mW and duration of 0.1 ms. LLLT was applied to three points. After three weeks of retention,
the rats were sacrificed and beheaded and the maxilla was evaluated by occlusal radiography, µ-CT,
and histomorphometric analyses. A comparison of the mean measurements between the groups was
performed using ANOVA and the Tukey post hoc test.
Results: Based on occlusal radiography and µCT, bone density in group B was significantly higher
than group A and group C (P<0.05). There was no significant difference in bone density between
group A and group C (P>0.05). Mean suture width (MSW) in group B was significantly lesser than
the control group (P=0.027) while there was no significant difference between MSWnin groups A
and B (P=0.116) and groups A and C (P=0.317).
Conclusion: It may be concluded that multiple low-power laser irradiation improves bone
regeneration after RPE while single irradiation does not have a positive effect
