Author/Authors :
Nasimi, Maryam Department of Dermatology - Autoimmune Bullous Disease Research Center - Razi Hospital - Tehran University of Medical Sciences, Tehran, Iran , Abedini, Robabeh Department of Dermatology - Autoimmune Bullous Disease Research Center - Razi Hospital - Tehran University of Medical Sciences, Tehran, Iran , Hallaji, Zahra Department of Dermatology - Autoimmune Bullous Disease Research Center - Razi Hospital - Tehran University of Medical Sciences, Tehran, Iran , Hosseinizade, Maryam Department of Dermatology - Autoimmune Bullous Disease Research Center - Razi Hospital - Tehran University of Medical Sciences, Tehran, Iran , Mohammadi, Fariba Department of Dermatology - Autoimmune Bullous Disease Research Center - Razi Hospital - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Background: Basal cell carcinoma (BCC) is the most common form of malignancy in white populations. It has been hypothesized that dietary factors may play a role in BCC development. In this
study, serum levels of folic acid and vitamin B12 were evaluated
in patients with BCC to investigate the potential role of these
vitamins in BCC development.
Methods: Forty-five BCC patients and 45 age- and sex-matched
healthy controls were enrolled in the study. Patients with a
history of radiotherapy in the affected area were excluded. All
participants completed a questionnaire including demographic
characteristics, and blood samples were taken to evaluate serum
levels of folic acid and vitamin B12.
Results: There were no significant differences in serum levels
of vitamin B12 and folic acid between healthy controls and BCC
patients. Serum levels of vitamin B12 were significantly higher
in female patients than male patients.
Conclusion: It seems that BCC is not related to serum levels of vitamin B12 and folic acid; however, this issue should be studied with larger sample sizes.
