Author/Authors :
Zartab, Hamed Pathology and Stem Cells Research Center - Afzalipour School of Medicine - Kerman University of Medical Sciences, Kerman, Iran - Center for Research and Training in Skin Diseases and Leprosy - Tehran University of Medical Sciences, Tehran, Iran , Iranmanesh, Behzad Pathology and Stem Cells Research Center - Afzalipour School of Medicine - Kerman University of Medical Sciences, Kerman, Iran , Amiri, Rezvan Pathology and Stem Cells Research Center - Afzalipour School of Medicine - Kerman University of Medical Sciences, Kerman, Iran , Shamsi-Meymansi, Simin Pathology and Stem Cells Research Center - Afzalipour School of Medicine - Kerman University of Medical Sciences, Kerman, Iran
Abstract :
Background: Alopecic and aseptic nodule of the scalp (AANS) is a rare entity characterized by the presence of sterile, culturenegative nodules/cysts and areas of non-scarring alopecia.
Methods: We describe a case on the vertex of a 26-year-old man
with a two-week history of a nodular, moderately-fluctuant, alopecic lesion. The patient also had cutis verticis gyrata (CVG).
Results: The aspirate culture was negative and histopathologic
findings were nonspecific. We also performed a trichoscopy of
the lesion. After eight weeks, the patient showed dramatic clinical
response to doxycycline and a dose of intralesional corticosteroid.
Conclusion: This is the first report of the simultaneous occurrence
of AANS and primary essential CVG. AANS is a probably
under-reported cause of non-scarring alopecia with a rapid and dramatic response to non-surgical treatment and a generally good prognosis.
