Author/Authors :
Asilian, Ali Department of Dermatology - Skin Diseases and Leishmaniasis Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Mozafarpoor, Samaneh Department of Dermatology - Skin Diseases and Leishmaniasis Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Goodarzi, Azadeh Department of Dermatology - Rasool Akram Medical Complex - Iran University of Medical Sciences, Tehran, Iran , Jafari, Mohammad Amin Department of Dermatology - Rasool Akram Medical Complex - Iran University of Medical Sciences, Tehran, Iran , Rajabi, Parvin Department of Pathology - School of Medicine - Khorshid Hospital - Isfahan University of Medical Sciences, Isfahan, Iran , Eftekhari, Mehdi Anatomical and Clinical Pathology Department - Azarmehr Medical Laboratory, Isfahan, Iran
Abstract :
Composite hemangioendothelioma (CHE) is a rare and little-known condition with combined benign, intermediate, and malignant features. In the current study, we describe the case of a young
female with the presentations of CHE, representing the second
known case in Iran. Also, we have comprehensively reviewed
previous case reports of CHE. A 30-year-old female was referred
with a reddish hemorrhagic painless mass in the small right
finger that appeared within a few days following trauma. The
mass was primarily excised but recurred within three weeks;
therefore, she underwent thorough clinical, laboratory, and
imaging studies. Finally, the lesions were biopsied and diagnosed
as CHE. Accordingly, the involved finger was amputated, and
the patient underwent chemoradiotherapy. Although CHE is a rare malignant condition worldwide, attention to the clinical
presentations of this malignancy can help scientists make better therapeutic approaches leading to the best outcomes.