Evaluation of Periodontal Status in Diabetes Mellitus Type 2 Patients Based on HbAlc and CRP

During the last decades, there has been an increasing interest in the relationship between diabetes inellitus (DM) and periodontitis. Some evidence has suggested that inflammatory factors like C-reactive protein (CRP) can be contributing factors to both periodontitis and diabetes. This study was ained at assessing periodontal position in diabetes mellitus type 2 patients based on HbAlc and CRP. Materials and Methods: 76 patients with diabetes mellitus 2 (DM2) were divided based on glycemic control: 35 subjects with HbAlc less than 7% and 41 subjects with HbA1c27%. The following measurements were conducled: Serum HbAlc and C-reaclive protein (CRP), gingival Index (GI), plaque Index (PI), clinical allachment loss (CAL), bleeding on probing (BOP), and probing depth (PD). Morcover, age, gender and duration of diabetes of the patients werc also analyzed. Results: In this study, 24 women and 11 men by mean age of 55/3128/37 were in a good diabetic patients' group (HbAlc<7%) and 30 females and 11 males by the mean age of 53/76+9/91 were in poor control diabetic patients (HbAlc27%). A significant correlation between the elevation of CRP and increased level of HbAlc was observed (P<0/001). The palicnls' age was associated with the duration of diabcles (P=0/024) and women had significantly more duration of diabetes than men (P=0/012). Regarding PD, CAL, BOP and PI, there was no significant difference between the analyzed groups. Also, no significant relationship between CRP and periodontal parameters has been found. Conclusion: CRP was found as a predictor of HbAlc in patients with poor glycemic control. This implies higher insection rales due lo diabetes.