Author/Authors :
Asanjarani, Behzad Department of Internal Medicine - Amir Alam Hospital - Tehran University of Medical Sciences, Tehran, Iran , Siri, Goli Department of Internal Medicine - Amir Alam Hospital - Tehran University of Medical Sciences, Tehran, Iran , Eshagh Hosseini, Mahmoud Department of Internal Medicine - Amir Alam Hospital - Tehran University of Medical Sciences, Tehran, Iran , Abdollahi, Hamed Department of Anesthesiology - Amir Alam Hospital - Tehran University of Medical Sciences, Tehran, Iran , Hasibi,Mehrdad Department of Internal Medicine - Amir Alam Hospital - Tehran University of Medical Sciences, Tehran, Iran , Erfanian, Reza Department of Ear - Nose and Throat (ENT) Diseases - Amir Alam Hospital - Tehran University of Medical Sciences, Tehran, Iran , Eshagh Hosseini, Mohammad Mehdi Department of Internal Medicine - Amir Alam Hospital - Tehran University of Medical Sciences, Tehran, Iran , Alesaeidi, Samira Rheumatology Research Center - Tehran University of Medical Sciences, Tehran, Iran , Asadollahi-Amin, Ali Iranian Research Center for HIV/AIDS - Iranian Institute for Reduction of High-Risk Behaviors - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Background: Routine blood testing consists of Complete Blood
Count (CBC) indices together with Comprehensive Metabolic Panel
(CMP) which have significant roles in both diagnosis and prognosis of
the novel coronavirus disease 2019 (COVID-19).
Methods: A total number of 942 COVID-19 patients and 400 healthy
persons as the control group were enrolled in this study. All patients
were admitted to a single center and were divided into two groups
according to disease severity (severe or non-severe). Routine laboratory
findings of peripheral blood sample were collected and then analyzed.
Results: Neutrophil-Lymphocyte Ratio (NLR) had the highest
sensitivity and specificity value for COVID-19 diagnosis. Among
patients with different severities of COVID-19, the amount of
neutrophil, NLR, platelet, hemoglobin, Red cell Distribution Width
(RDW) and total bilirubin was significantly different (p<0.01).
Conclusion: Some indices of complete blood count and comprehensive
metabolic panel have diagnostic and prognostic roles in COVID-19
patients, which are helpful in early diagnosis, predicting severity and
adverse outcomes of patients with COVID-19.
Keywords :
COVID-19 , Erythrocyte indices , Hematologic tests , Humans , Lymphocytes , Neutrophils
