Title of article :
Comparison of Green Tea and Metformin Effects on Anthropometric Indicators in Women with Polycystic Ovarian Syndrome: A Clinical Trial Study
Author/Authors :
Farhadian, Maryam Research Center for Health Sciences - Hamadan University of Medical Sciences, Hamadan, Iran, , Barati, Somayeh Faculty of Basic Sciences - Islamic Azad University Hamadan Branch, Hamadan, Iran , Mahmoodi, Minoo Faculty of Basic Sciences - Islamic Azad University Hamadan Branch, Hamadan, Iran , Barati Mosleh, Amir Endometrium and Endometriosis Research Center - Hamadan University of Medical Sciences, Hamadan, Iran , Yavangui, Mahnaz Endometrium and Endometriosis Research Center - Hamadan University of Medical Sciences, Hamadan, Iran
Abstract :
Background: Polycystic ovary syndrome (PCOS), as a complex reproductive and endocrinological
disorder, affects up to one in five women. Treatment for obesity in women with this syndrome is necessary
due to the occurrence of various complications, especially infertility. Recently, green tea with many
health benefits, as a natural herbal medicine, has been widely considered in treating various diseases.
Objective: This clinical study was planned to compare the effect of green tea and metformin treatment
on the anthropometric indices of women with PCOS. Materials and Methods: In this double-blind,
randomized clinical trial, 45 women among 18–35 years of age with PCOS referring to the endometriosis
center of Fatemieh Hospital of Hamadan, Iran, who had the eligibility criteria for entering the study, were
randomized into three study groups: the green tea, the metformin group, and the control group. Weight,
body mass index (BMI), waist circumference, hip circumference, and waist-to-hip ratio, before, 1 month
later, and 3 months after intervention in each group were measured. Data were statistically analyzed
using Statistical Package for the Social Sciences (SPSS) statistical software, version 23.0. Results: No
statistically significant difference was observed between the three groups during the study period. A
significant reduction of anthropometric indices, such as weight, BMI, waist, and hip circumference, was
observed in the green tea group. Conclusion: The use of green tea for patients with PCOS is recommended
as a complementary therapy that can have potential effects on obesity.
Keywords :
Anthropometric indices , green tea , metformin , polycystic ovary syndrome , randomized controlled trials
Journal title :
Journal of Reports in Pharmaceutical Sciences