Title of article :
Synthesis, Characterization and Antibacterial Activity of Some New Oxazepine compounds
Author/Authors :
mohammed-ali, munther abdul-jaleel mohammed basrah university - college of pharmacy - department of pharmaceutical chemistry, Iraq , salman, hussam hamza basrah university - college of pharmacy - department of pharmaceutical chemistry, Iraq , abdul-hussein, zainab radhi basrah university - college of science - department of biology, Iraq
Abstract :
Four new 1,3-oxazepine compounds have been prepared by cycloaddition of synthesized bis-Schiff bases with maleic anhydride in toluene. The Schiff bases were prepared by the condensation of ethylene diamine with two equivalents of some aldehydes. The structure of the oxazepines were confirmed via elemental analysis,FT-IR and, :H-NMR spectra. The compounds were screened for their antibacterial activity against gram negative bacteria (Escherichia coli) and gram positive (Staphylococcus aureus). The results showed that the examined compounds exhibited varied antibacterial activity in comparison with the standard drugs.
Keywords :
1 , 3 , oxazepine , Schiff base , cycloaddition , and antibacterial activity.
Journal title :
Journal of Thi-Qar Science
Journal title :
Journal of Thi-Qar Science
