Title of article :
Chemical composition and cytotoxicity of the essential oil of Tanacetum abrotanifolium (L.) Druce (Asteraceae) from Iran
Author/Authors :
Sonboli ، Ali Department of Biology - Medicinal Plants and Drugs Research Institute - Shahid Beheshti University , Ghilichpour ، Sepideh Islamic Azad University, Pharmaceutical Sciences Branch , Farhadpour ، Mohsen Department of Plant Bioproducts - National Institute of Genetic Engineering and Biotechnology (NIGEB) , Arman ، Mitra Department of Biology - Payame Noor University
Abstract :
Chemical composition of the essential oil obtained from aerial parts of Tanacetum abrotanifolium (L.) Druce (Asteraceae) was investigated. Plant sample was collected at full flowering stage from West Azerbaijan Province of Iran. The hydrodistilled essential oil was analyzed by GC-FID and GC-MS. The major compounds were found to be (E)-sesquilavandulol (26.6%), camphor (16.2%) and 1,8-cineole (12.9%). Cytotoxicity activity of the oil was evaluated against four cancer cell lines, of which IC50 values estimated to be 312, 312, 625 and 1250 μg oil/mL for the monkey kidney Vero, human breast adenocarcinoma (MCF7), choriocarcinoma (JET 3) and human colon adenocarcinoma (SW480) cell lines, respectively.
Keywords :
Aerial parts , Asteraceae , Cytotoxicity activity , Essential oil , GC , MS analysis , Tanacetum abrotanifolium
Journal title :
Trends In Phytochemical Research
Journal title :
Trends In Phytochemical Research
