Determination of the prevalence of clinical signs of Aspirin and NSAID poisoning in patients referring to Ahvaz Razi Hospital

Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of drugs that are among the most commonly prescribed drugs worldwide. Due to the ease of access and widespread use of these drugs, many cases of intentional and accidental poisoning of these compounds have been reported. The aim of this study was to determine the prevalence of the clinical signs of drug toxicity with aspirin and NSAIDs in patients referred to Razi Hospital in Ahwaz. Methods: In this study, patients suffering from aspirin and NSAIDs poisoning referred to Razi Hospital during 2013-2015 were included in the study. Information reviewed from their stored records includes clinical presentation, demographic information, reference data, and treatment options. Results: In this study, 79.5% were female respondents and 20.5% were male, and Faye and Kramer coefficients confirmed the existence of a strongly separate relationship between the gender variable and the first clinical signs of poisoning. The results showed that Diclofenac with 27% had the highest toxicity and nausea was the most common symptom in all drug toxicity with aspirin and NSAIDs. Nausea is a common symptom of poisoning with these drugs. There was a significant relationship between laboratory changes with the type of drug and the need for ICU admission, and this relationship was not strong due to the index values. Conclusion: According to the results, most of the patients were aged between 14-24 years old. Nausea was the most common symptom in all drug toxicity with aspirin and NSAIDs.