Author/Authors :
Sharifi, Hooman Tobacco Prevention and Control Research Center - National Research Institute of Tuberculosis and Lung Diseases (NRITLD) - Shahid Beheshti University of Medical Sciences ,Tehran, Iran , Ghanei, Mostafa Chemical Injuries Research Center - Systems Biology and Poisonings Institute - Baqiyatallah University of Medical Sciences, Tehran, Iran , Jamaati, Hamidreza Chronic Respiratory Diseases Research Center - NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran , Masjedi, Mohammad Reza Tobacco Control Research Center, Iranian Anti Tobacco Association, Tehran, Iran , Najafimehr, Hadis Gastroenterology and Liver Diseases Research Center - Research Institute for Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Fakharian, Atefeh Chronic Respiratory Diseases Research Center - NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran , Aryanpour, Mahshid Tobacco Prevention and Control Research Center - National Research Institute of Tuberculosis and Lung Diseases (NRITLD) - Shahid Beheshti University of Medical Sciences ,Tehran, Iran , Sonia Buist, A. Division of Pulmonary and Critical Care Medicine - Oregon Health and Science University, Portland, Oregon
Abstract :
Background: Chronic obstructive pulmonary disease (COPD) has been the
third leading cause of morbidity and the sixth leading cause of mortality in
2020. This chronic disease usually impairs health status and is an independent
predictor of morbidity and mortality. The main objective of this study was to
assess health-Related quality of life (HRQL) in a large sample of participants
with and without COPD.
Materials and Methods: The present study was based on the data obtained
from the population-based BOLD study in Iran. The sampling frame in this
study included the whole population of 31 provinces of Iran. Participants were
recruited using a stratified cluster sampling strategy with proportional
allocations within strata. All the participants were requested to fill the Short
Form 12 (SF-12) Health Survey Questionnaire, an abbreviated version of the SF-
36.
Results: A total of 1062 subjects, including 479 (45%) males and 583 (54.7%)
females, were enrolled in the study. The mean age of the participants was
40±15.04 years. The overall COPD prevalence based on the post-bronchodilator
spirometry functional criteria was 5.0%. The mean PCS- 12 and MCS- 12 for all
the subjects were 66.61±22.72 and 60.79±23.52, respectively. The mean scores of
PCS and MCS were significantly lower in patients with COPD than those
without COPD (P<0.001).
Conclusion: The findings of this study demonstrated that COPD, female
gender, and an age above 40 years influenced HRQL, especially the physical
dimension, as shown by the SF-12 instrument.
Keywords :
Chronic obstructive pulmonary disease , Epidemiology , Health-related quality of life , Iran
