The effect of Boldenone and Aerobic Training with Jujube Extract and Gallic Acid on Glutathione Peroxidase and Catalase in Heart Tissue of Male Wistar Rats

The aim of this study was to investigate the effect ofboldenone and aerobic training with Jujube extract and Gallic acid on glutathione peroxidase and catalase in beaii tissue ofmale Wistar rats. Thus, 42 male Wistar rats aged 8-12 weeks (weight 195±7.94g) were randomly divided into 7 groups: control, boldenone (Smg/kg),jujube (Ziziphusj11juba) extract+ boldenone, Gallic acid + boldenone, endurance training+ boldenone, endurance training+ Ziziplws juj11ba extract+ boldenone, and endurance training+ Gallic acid+ boldenone. Endurance training protocol was performed 5 days a week for 8 weeks, each session 60 minutes at 25 to 30 meters per minute. Injection once a week, on an appointed day, and in the hamstring wa8 conducted i.n depth. Aller anesthesia, autopsy was performed and the cardiac tissue isolated. Data were analyzed using t­test, one way A NOVA and Scheffe post hoc at the P < 0.05. The results showed that there was a significant differences between catalase in tbc various groups (P = 0.000). Catalasc expression in boldcnonc +training+ Gallic acid increased significantly compared to the boldenone (P = 0.000) and control (P = 0.000) group. Also, there was a significant differences between glutathione peroxidase in the various groups (P = 0.000). Glntathione peroxidase expression significantly increased in boldenone +training+ jujube compared to the boldenone (P = 0.000) and control (P = 0.000) group. According to the findings, it seems that boldcnonc iqjcctcd with jujubeextrnct/Gallic acid and perfonning endurance training for 8 weeks have beneficial effects on antioxidant system.