Author/Authors :
Mirzapour, Mohaddese Department of Persian Medicine - School of Persian Medicine Babol University of Medical Sciences, Babol ,Iran , Mojahedi, Morteza Department of Persian Medicine - School of Persian Medicine Babol University of Medical Sciences, Babol ,Iran , Shokri, Javad Research Center for Infectious Diseases and Tropical Medicine - Health Research Center - Babol, University of Medical Sciences, Babol, Iran , Khafri, Soraya Department of Statistic and Epidemiology - School of Medicine - Babol University of Medical Sciences, Babol, Iran , Memariani, Zahra Department of Persian Medicine - School of Persian Medicine Babol University of Medical Sciences, Babol ,Iran
Abstract :
Functional dyspepsia (FD) is a highly prevalent condition with high impact on healthcare costs. Considering the complimentary therapies options like phytotherapy, this study aimed to investigate the efficacy
and safety of Nardostachys jatamansi (D.Don) DC. extract in sixteen FD patients. The subjects received
capsules of 500 mg N. Jatamansi, 3 times daily before meals for 30 days. The severity of early satiation
and postprandial fullness were assessed by self-report of improvement at least 50% of symptoms and
other FD symptoms assessed by Gastrointestinal Symptom Rating Scale (GSRS) before intervention
and at end of treatment. The mean GSRS score level decreased significantly after intervention among
study population. Five patients had chief complaint of early satiety and post prandial fullness who all of
them reported 50% improvement. According to the results N. jatamansi seems to be effective in patients
with refractory FD. Randomized clinical studies seem to be required
Keywords :
Dyspepsia , Traditional medicine , N. jatamansi , Herbal medicine
