Title of article :
Importance of IL-1β in SARS-CoV-2 infection
Author/Authors :
Behboudi ، Emad Golestan University of Medical Sciences , Teimouri ، Hossein Golestan University of Medical Sciences , Hamidi-Sofiani ، Vahideh Department of Microbiology - Golestan University of Medical Sciences , Memarian ، Ali Golestan University of Medical Sciences
Abstract :
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provokes the host immune responses and induces severe respiratory syndrome by overreaction of immune cells. IL-1β is a pro-inflammatory cytokine highly associated with the related inflammation and cytokine storm, and several IL-1β antagonists are being used to treat cytokine release syndrome (CRS). Accordingly, some studies and clinical trials are investigating the effects of IL-1β antagonists for controlling Coronavirus disease 2019 (COVID-19) associated CRS. Here, we will review any interaction and association between IL-1β and SARS-CoV-2 infection.
Keywords :
COVID , 19 , Cytokine storm , IL , 1β , Inflammation , SARS , CoV2
Journal title :
International Journal of Pediatrics
Journal title :
International Journal of Pediatrics
