Correlation of Calcium/Potassium and Zinc/Copper Coefficients with Bio Elements in Pre-obese Pateints

The expression micro-elements refers to the fundamental particles existed in biological material in very small amounts. The chronic deficiency of essential microelements in the body leads to the development of pathological problems and morphological changes as a result of a defect in the cellular metabolism process. The aim of the work is to assess the levels and correlations of bio-elements and their coefficients in pre-obese patients. Biomaterial hair samples were taken to characterize the formation of bioelement imbalances among young groups of (100) patients over (18) years old with BMI = (18-24.9) and BMI = (25-29.9). For the first time, the feasibility of using the X-ray fluorescence analysis to monitor the balance of macro-and microelements in the body was demonstrated. In the overweight group of males and females, the values of calcium/potassium coefficient and zinc/copper coefficient are higher than the normal values, as well as an imbalance in the binding of bio-elements with each other and their levels compared with the normal group which leads to a violation of the cellular metabolism process. Bio-elements should not be considered separately since their interaction together produces a biological effect of a new quality. The calcium/potassium ratio can be taken as an indicator of weight gain. The discovered imbalance of macro-and microelements in young patients living in Grodno, Belarus in terms of calcium, zinc, iron, copper, and potassium will allow for the early nutritional correction.