Title of article :
A Rare Case of Cardiac Metastasis from Colon Cancer
Author/Authors :
Modabber ، Zahra Clinical Research Development Unit - Student Committee Research, Rouhani Hospital - Babol University of Medical Sciences , Pourkia ، Roghayeh Clinical Research Development Unit - Rouhani Hospital - Babol University of Medical Sciences , Vafaey ، Hamidreza Clinical Research Development Unit - Rouhani Hospital - Babol University of Medical Sciences , Alizadeh ، Ali Clinical Research Development Unit - Rouhani Hospital - Babol University of Medical Sciences , Ranaei ، Mohammad Clinical Research Development Unit - Cellular and Molecular Biology Research Center, Health Research Institute, Rouhani Hospital - Babol University of Medical Sciences
Abstract :
It is very rare for colorectal neoplasms to metastasize to the heart in the worldwide medical literature; only a single case of well-documented colorectal cancer metastasis to the left atrium was found. The case of a 66-year-old man is explained in this paper, who was suffering from metastatic adenocarcinoma of the colon that included the left atrium. In transthoracic and transesophageal echocardiography, a large multilobulated mass was present in the left atrium. An accidental pulmonary mass was also seen in a lung spiral CT scan. The cardiac mass was taken out, and a biopsy was obtained from the pulmonary mass. Adenocarcinoma was seen in histological assessment. Immunohistochemical staining was carried out to examine the expression of cytokeratin 7, cytokeratin 20, and caudal-related homeobox transcription factor 2 (CDX2) to determine the origin of the adenocarcinoma. In addition, the expression of these proteins was linked to the attributes of the patient and tumor. Post-surgery transesophageal echocardiography showed normal left ventricle and right ventricle function with no evidence of left atrium mass. Therefore, we suggest that asymptomatic cancer patients with a history of colorectal cancer and who have developed cardiac symptoms should be immediately examined for potential cardiac metastasis.
Keywords :
Cardiac metastasis , Colorectal Neoplasms , Heart , Left atrium , Metastatic adenocarcinoma
Journal title :
Iranian Journal of Pathology (IJP)
Journal title :
Iranian Journal of Pathology (IJP)