Title of article :
Prevalence of Human T-Lymphotropic Virus Type 1 in Brain-Dead Organ Donors
Author/Authors :
Nasri ، Elahe Infectious Diseases and Tropical Medicine Research Center - Isfahan University of Medical Sciences , Fakhim ، Hamed Infectious Diseases and Tropical Medicine Research Center - Isfahan University of Medical Sciences , Jafari Sales ، Abolfazl Department of Microbiology - School of Basic Sciences - Islamic Azad University, Kazerun Branch , Bannazadeh Baghi ، Hossein , Vaezi ، Afsane Department of Medical Laboratory Sciences - School of Allied Medical Sciences - Iran University of Medical Sciences , Rezaei ، Mitra Virology Research Center, National Research Institutes of Tuberculosis and Lung diseases (NRITLD) - Shahid Beheshti University of Medical Sciences , Tabarsi ، Payam Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD) - Shahid Beheshti University of Medical Sciences
Abstract :
Background: This study aimed to assess the prevalence of human T-lymphotropic virus type 1 (HTLV-1) among brain-dead organ donors at Masih Daneshvari Hospital in Tehran, Iran. Methods: By enzyme-linked immunosorbent assay (ELISA), 54 organ donors were screened for HTLV-1 virus in this descriptive cross-sectional study. Following that, Western blot confirmation was performed to confirm the HTLV-I infection. Results: Anti-HTLV-1 antibodies were detected in 2 (3.4%) cases out of 54 patients tested by ELISA. A western blot was performed in cases of positive results, but none of the subjects tested positive for HTLV-1 infection. Conclusions: The results of the present study indicated rare cases of HTLV-I infection in brain-dead organ donors. However, it is recommended that organ donors be investigated for the prevalence of this virus.
Keywords :
HTLV , 1 , Organ Donors , ELISA , Western Blot
Journal title :
Archives of Clinical Infectious Diseases
Journal title :
Archives of Clinical Infectious Diseases
