Title of article :
Assessment of Educational Intervention Effects on the Level of Oxidative Stress Parameters and Performance in Oncology Staff
Author/Authors :
Riazat ، Afsaneh Department of Occupational Health Engineering - School of Public Health and Safety - Shahid Beheshti University of Medical Sciences , Akbari ، Mohammad Esmaeil Cancer Research Center - Shahid Beheshti University of Medical Sciences , Farhang ، Somayeh Department of Occupational Health Engineering - School of Public Health and Safety - Shahid Beheshti University of Medical Sciences , Rakhshanderou ، Sakineh Department of Public Health - School of Public Health and Safety - Shahid Beheshti University of Medical Sciences , Mirzaei ، Hamidreza Department of Radiotherapy - School of Medicine Shohada-e-Tajrish Hospital - Shahid Beheshti University of Medical Sciences , Azadeh ، Payam Department of Radiation Oncology - School of Medicine - Shahid Beheshti University of Medical Science , Rezazadeh Azari ، Mansour Department of Occupational Health Engineering - School of Public Health and Safety, Safety Promotion and Prevent of Injuries Research Center, School of Public Health - Shahid Beheshti University of Medical Sciences , Panahi ، Davoud Department of Occupational Health Engineering - School of Public Health and Safety - Shahid Beheshti University of Medical Sciences
Abstract :
Background: Occupational exposure to antineoplastic drugs causes the production of free radicals and their reaction with macromolecules in the body. Objectives: The present study was conducted to evaluate the effectiveness of the educational intervention by using urinary oxidative stress indices of the oncology staff in Iranian hospitals. Methods: Healthy full-time oncology and pharmacy staff (n = 45) participated in this prospective interventional study. The training of the personnel for proper handling of the antineoplastic drugs was given. During their work shift, their performance was recorded in a checklist. Urinary oxidative stress indices of the staff and scores of their performances were obtained before and after their training. Results: The mean performance score of all oncology staff was statistically higher than after 2 months of educational intervention (P 0.001). The mean activity levels of Superoxide Dismutase and Catalase enzymes of all oncology staff was statistically lower than after 2 months of educational intervention (P 0.001). The mean level of Malondialdehyde of all oncology staff was statistically lower than after 2 months of educational intervention (P 0.05). Conclusions: Educational intervention increased oncology staff performance score and it affected the level of the oxidative stress parameters 2 months after the educational intervention by decreasing the activity of enzymes and the level of malondialdehyde.
Keywords :
Biological Monitoring , Oncology Staff , Educational Interventions , Performance , Stress Oxidative
Journal title :
International Journal of Cancer Management
Journal title :
International Journal of Cancer Management
