Prevalence of Diabetic Nephropathy in Patients with Type 1 Diabetes in Iran: A Systematic Review and Meta-Analysis

Background: Diabetic nephropathy (DN) is one of the complications of diabetes. The present study was conducted with the aim of determining the prevalence of DN in patients with D1T in Iran. Methods: This meta-analysis and systematic review included the articles published from 2000 to 2022, in domestic (Iran) and international journals. Search keywords included diabetes, type 1 diabetes, D1T, nephropathy, Iran, children, and adolescents, which were searched in Persian and English. The search was conducted by two members of the research team independently and the outcomes were finally approved by the third person who was considered as the manager of the research team. The extracted data was analyzed by CMA3 software. Results: The overall prevalence of DN was found to be 10% (confidence interval (CI) = 3.4-26.1). The lowest and highest prevalences of DN were found to be reported as 0.04% and 30.8%, respectively. Conclusion: Considering the high prevalence of DN in patients with T1DM, it is suggested that the necessary preventive measures be taken to reduce the complications of diabetes in these patients