Title of article :
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
Author/Authors :
Hassannejad ، Sahar Medical Laboratory Science Department - Knowledge University , Ghamari ، Reza Genome research center - National Institute of Genetics Engineering and Biotechnology , Saremi ، Mohammad Ali Personalized Medicine Research Center of AmitisGen , Shojaei Baghini ، Sadegh Agriculture Biotechnology Department - National Institute of Genetics Engineering and Biotechnology
Abstract :
Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and disrupts the connections between Sertoli and spermatogonia cells at base layers. Moreover, vitamin D is very important in the reproductive system of men. In this study, the effect of vitamin D on biosulfur-induced azoospermia in mice was investigated. The results showed an increase in the quality of sperm parameters in the group treated with vitamin D.
Keywords :
Vitamin D , Cancer , Busulfan , infertility , Sperm parameters
Journal title :
Personalized Medicine Journal
Journal title :
Personalized Medicine Journal
