Title of article :
Successful En-Bloc Kidney Transplantation from a 5-year-Old Donor with Cerebral Palsy to a 60-Year Old Recipient: A Case Report
Author/Authors :
Khorrami ، Mohammad Hatef Department of Medicine - Isfahan University of Medical Sciences , Dehghani ، Sanaz Organ procurement unit of Sina hospital - Tehran University of Medical Sciences , Mashhadi ، Rahil Urology Research Center - Tehran University of Medical Sciences , Abdi ، Hossein Urology Research Center - Tehran University of Medical Sciences , Namdari ، Farshad Aja university of medical sciences
Abstract :
Introduction There are a growing number of unmet kidney donor sources. So, alternative donor sources, such as donation after circulatory determination of death (DCDD), are taken into the consideration.Case presentationIn this study, we represent successful En-Bloc kidney transplantation from a 4-year-Old donor with cerebral palsy to a 60-year old recipient. The kidney of a 4-year-old boy with congenital CP (weight=12Kg; BMI=12) with brain death was transplanted to a 60-year-old man (weight =70Kg; BMI=23.6). Panel-reactive antibody (PRA) to HLA class I (PRA I) and HLA class II (PRA II) were observed less than 5% in the 60-year old recipient. Also, the PRA titer with complement-dependent cytotoxicity (PRA-CDC) and the donor-recipient WBC crossmatch was negative. Our case is reported by a successful EKBT to an adult with the en-bloc kidney of a 4-year-old child with cerebral palsy. The small kidneys of a cerebral palsy child are adapting and functioning well in the adult body.ConclusionsTherefore, CP pediatric donors can be good resources for transplantation whenever available.
Keywords :
kidney transplant , pediatric donors , Organ donation , Circulatory Determination of Death
Journal title :
Translational Research in Urology
Journal title :
Translational Research in Urology