Title of article :
Onset of Mania by Vitamin B12 Injection in a 52-Year Old Patient with Refractory and Resistant Depression
Author/Authors :
Artoonian ، Valentina Department of Psychiatry - Tehran University of Medical Sciences , Aghamollaii ، Vajiheh Department of Neurology - Tehran University of Medical Sciences , Nadjarzadeh ، Azadeh Department of Nutrition - Nutrition and Food Security Research Center, School of Public Health - Shahid Sadoughi University of Medical Sciences , Bidaki ، Reza Research Center of Addiction and Behavioral Sciences, Diabetes Research Center - Shahid Sadoughi University of Medical Sciences
Abstract :
Vitamin B12 affects and modify the function of multiple organ systems. Its deficiency may cause psychiatric symptoms in addition to hematologic, gastrointestinal, and neurologic manifestations. The present case study aims to report a patient with vitamin B12 deficiency who coexisted with resistant and persistent depression, and experienced mania phase after the replacement of vitamin B12. For a patient with refractory and resistant depression and evidence or a risk factor for vitamin B12 deficiency, it is required to check plasma levels and monitor psychiatric symptoms during vitamin B12 supplementation. There are some manifestations of B12 deficiency including bipolar disorder, mood lability, irritability, and psychosis due to deficiency but we didn’t find case report about induce of psychiatric presentation follow correction of vitamin B12 deficiency
Keywords :
Refractory depression , Bipolar disorder , Vitamin B12 deficiency
Journal title :
Journal of Nutrition and Food Security (JNFS)
Journal title :
Journal of Nutrition and Food Security (JNFS)
