Antimicrobial Activity and Synthesis of Thiazole Derivatives: A Recent Update

One of the new global health risks is antimicrobial medication resistance. The creation of new and potent antimicrobial drugs is urgently needed due to the high mortality rate of this menace. One of the five-membered aromatic heterocycles subjected to the most inspection is the thiazole class. When it comes to therapeutic agents’ antimicrobial action, the thiazole moiety is typically used as a fundamental framework. Many natural and synthetic thiazole derivatives have been found to exhibit significant biological activities. The current review gives a general overview of various thiazole synthesis techniques and describes various compounds with thiazole moiety with antimicrobial activity, which encourages further investigation into the development of thiazole-containing antimicrobial drugs.