Title of article
Inhibition of bacterial adhesion and anti-biofilm effects of Bacillus cereus and Serratia nematodiphila biosurfactants against Staphylococcus aureus and Pseudomonas aeruginosa
Author/Authors
Keyhanian ، Alireza Infectious Diseases Research Center - Aja University of Medical Sciences , Mohammadimehr ، Mojgan Infectious Diseases Research Center - Aja University of Medical Sciences , Nojoomi ، Farshad Infectious Diseases Research Center - Aja University of Medical Sciences , Naghoosi ، Hamed Infectious Diseases Research Center - Aja University of Medical Sciences , Shakouri Khomartash ، Mehdi Medical Biotechnology Research Center - Aja University of Medical Sciences , Chamanara ، Mohsen Toxicology Research Center - Aja University of Medical Sciences
From page
425
To page
432
Abstract
Background and Objectives: Biosurfactants are amphiphilic surface-active agents that mainly produced by various microorganisms. In this study, the anti-biofilm and inhibition of bacterial adhesion activities of two bacterial biosurfactants were investigated. Materials and Methods: After extraction and evaluation of Bacillus cereus and Serratia nematodiphila biosurfctants, inhibition of bacterial adhesion and anti-biofilm effects of them on Staphylococcus aureus and Pseudomonas aeruginosa were determined. Results: On average, the synergistic effect of two bacterial biosurfactants, caused about 60% decrease in adhesion and about 80% decrease in biofilm formation of S. aureus and P. aeruginosa. Conclusion: The results of this study showed that combination of B. cereus and S. nematodiphila biosurfactants would increase the potential of attachment inhibition and biofilm eradication with very low toxicity.
Keywords
Bacterial adhesion , Biofilms , Bacillus cereus , Surface , active agents , Staphylococcus aureus , Pseudomonas aeruginosa
Journal title
IJM Iranian Journal of Microbiology
Journal title
IJM Iranian Journal of Microbiology
Record number
2745902
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