A randomized control trial comparing the efficacy of 3Mixtatin andModified 3Mix‑MP paste using lesion sterilization and tissue repairtechnique to conventional root canal treatment in primary molarsof children aged 4–8 years: An in vivo study

Background: The aim of this study was to evaluate clinical and radiographic success rates of3Mixtatin and Modified 3Mix‑MP paste and compare it with conventional root canal treatmentprocedure in primary molars requiring pulpectomy.Materials and Methods: In this in vivo study, 66 primary molars in 52 children aged between 4and 8 years with primary molars having chronic periapical abscess were treated randomly with3Mixtatin, Modified 3Mix‑MP paste, and Metapex. The subjects were reviewed at 6 and 12 monthsboth clinically and radiographically after pulpal therapy to evaluate and compare the healing process.The data obtained were subjected to statistical analysis at a significance level of 0.05.Results: By the end of 12‑month follow‑up among the three groups, Group I seemed to beperforming consistently better as compared to the other two groups when evaluated clinically andradiographically. However, Group III resulted in the greatest number of failures, with success ratebeing mere 42.9% at the end of follow‑up period.Conclusion: Radiographic and clinical healing occurred in all the three groups; however, basedon our results, Group I seemed to be performing consistently better among the three groups at12‑month follow‑up. Hence, it can be inferred that 3Mixtatin used as a localized agent is effectiveand comparable to both Modified 3Mix‑MP paste and conventional pulpectomy procedure involvingcalcium hydroxide and iodoform paste in primary teeth.