Title of article :
Current Advances in Nanotechnology-Mediated Delivery of Herbal and Plant-Derived Medicines
Author/Authors :
Jalili ، Amir Department of Pharmaceutical Technology - Faculty of Pharmacy - Eastern Mediterranean University , Bagherifar ، Rafieh Department of Pharmaceutics - Student Research Committee, Faculty of Pharmacy - Tabriz University of Medical Sciences , Nokhodchi ، Ali Pharmaceutics Research Laboratory - School of Life Sciences - University of Sussex , Conway ، Barbara Department of Pharmacy - School of Applied Sciences, Institute of Skin Integrity and Infection Prevention - University of Huddersfield , Javadzadeh ، Yousef Biotechnology Research Center, Faculty of Pharmacy - Tabriz University of Medical Science
Abstract :
Phytomedicine has been used by humans since ancient times to treat a variety of diseases. However, herbal medicines face significant challenges, including poor water and lipid solubility and instability, which lead to low bioavailability and insufficient therapeutic efficacy. Recently, it has been shown that nanotechnology-based drug delivery systems are appropriate to overcome the above-mentioned limitations. The present review study first discusses herbal medicines and the challenges involved in the formulation of these drugs. The different types of nano-based drug delivery systems used in herbal delivery and their potential to improve therapeutic efficacy are summarized, and common techniques for preparing nanocarriers used in herbal drug delivery are also discussed. Finally, a list of nanophyto medicines that have entered clinical trials since 2010, as well as those that the FDA has approved, is presented.
Keywords :
Phytomedicine , Herbal drug , Nanotechnology , Drug delivery systems , Nanophytomedicine
Journal title :
Advanced Pharmaceutical Bulletin
Journal title :
Advanced Pharmaceutical Bulletin
