Review of Lifespan Diagnosis in Patients with Substance-induced Psychosis Admitted to Psychiatric Wards of Imam Hussein Hospital

Background and Aim: Diagnostic certainty is difficult in the early stages of psychotic disorders, and it becomes more complicated if at the same time alcohol or drugs get consumed. There is a bilateral association between substance use and psychotic symptoms. Thus, this study was aimed to evaluate the lifespan diagnosis in patients with substance-induced psychosis admitted to psychiatric wards of Imam Hussein Hospital in Tehran 2015. Materials and Methods: This cross-sectional study was conducted on 90 patients diagnosed with substance-induced psychosis in the psychiatric wards of Imam Hussein Hospital in 2015 in Tehran. The data were analyzed through frequency descriptive statistics and charts and by logistic regression using SPSS23 software. Results: In patients with substance-induced psychosis, the results showed that bipolar disorder with psychotic symptoms was the most common disorder (48.9%), followed by schizoaffective (36.7%) disorder, schizophrenia (22.2%), personality disorders (16.6%) (Antisocial, 5.5%; borderline personality disorder (BPD), 11.1%), adult attention-deficit/hyperactivity disorder (ADHD) (3.3%), obsessive-compulsive disorder (OCD) (4.4%), and post-traumatic stress disorder (PTSD) (1.1%). Logistic regression results showed that the patients age and family history of psychotic disorders could significantly predict the transition to the spectrum of primary psychotic disorders. Conclusion: In psychotic patients or those with primary psychosis, the simultaneous consumption of several substances may indicate a further aggravation of the disease and accelerate the transition of their diagnosis. The evolution of the diagnosis of substance-induced psychosis into primary schizophrenia should be considered in the treatment and administration of the drugs.