Mortality among COVID-19 Patients with Different Comorbidities in Kermanshah, West of Iran (2020)

Background: Cancer and underlying diseases in the covid-19 pandemic created more problems for those affected by the coronavirus. This study aimed to evaluat patients’ mortality and related factors based on underlying diseases in people with COVID-19. Materials and Methods: This descriptive study was performed on patients with COVID-19 admitted to Kermanshah hospital from February 22, 2020, to September 22, 2021. Clinical information was obtained from medical records and patient’s history was extracted from the case documentation. The mortality and case fatality rates in hospitalized COVID-19 cases were calculated. Analysis of logistic regression models was used to identify prognostic factors of death. Results: Out of 55813 patients admitted to the hospital due to covid-19 on the mentioned date, 4260 died. Furthermore, the most common underlying disease in hospitalized patients due to covid 19 was hypertension (11.4%). The prevalence of cancers was 1.4%. The highest in-hospital case fatality rate was chronic kidney disease (CKD) (21.3%) and cancer (16.6%). In addition, among the underlying diseases, the odds ratio of CKD was 2.12 (CI90%= 1.38- 3.26), and cancers were 2.06 (CI95%= 1.25- 3.37), the most important underlying diseases for odds of death. Conclusion: The prevalence of hypertension (HTN) and cardiovascular diseases (CVD) was higher in hospitalized patients with COVID-19 than patients with other underlying diseases. However, patients with CKD and cancer had a higher odds ratio for death. Therefore, attention to managing patients with CKD and cancers should be seriously considered and followed.