Author/Authors :
Tajdari ، Mahnaz Department of Clinical Toxicology - Toxicological Research Center, School of Medicine, Loghman Hakim Hospital, Toxicological Research Center - Shahid Beheshti University of Medical Sciences , Amiri ، Farbod Department of Clinical Toxicology - School of Medicine - Shahid Beheshti University of Medical Sciences , Rahimi ، Mitra Department of Clinical Toxicology - Toxicological Research Center, School of Medicine, Loghman Hakim Hospital, Toxicological Research Center - Shahid Beheshti University of Medical Sciences , Ohadi ، Laya Department of Clinical Toxicology - School of Medicine - Shahid Beheshti University of Medical Sciences , Ghorbani ، Fariba Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences , Shadnia ، Shahin Department of Clinical Toxicology - Toxicological Research Center, School of Medicine, Loghman Hakim Hospital, Toxicological Research Center - Shahid Beheshti University of Medical Sciences , Talab Evini ، Peyman Erfan Department of Clinical Toxicology - Toxicological Research Center, School of Medicine, Loghman Hakim Hospital, Toxicological Research Center - Shahid Beheshti University of Medical Sciences
Abstract :
Background: Alcohol toxicity is a significant medical emergency with implications for patient management and outcomes. This single-blinded randomized intervention study investigated the effects of oral probiotics on various laboratory parameters in patients with acute alcohol toxicity. Methods: A total of 30 eligible patients were randomly assigned to either the control (placebo) or intervention (oral probiotics) group. Results: While the study did not reveal a significant impact on the length of hospital stay (LOHS), it did demonstrate notable improvements in laboratory variables, including pH, serum glutathione level, serum vitamin B6 level, and O2 saturation, in the probiotic group. Conclusion: These findings suggest the potential benefits of probiotics in mitigating certain aspects of alcohol toxicity.
