Author/Authors :
Abtahi ، Naeimeh Sadat Department of Embryology - Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine - Academic Center for Education, Culture and Research (ACECR) , Ebrahimi ، Bita Department of Embryology - Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine - Academic Center for Education, Culture and Research (ACECR) , Ghaffari ، Firouzeh Department of Endocrinology and Female Infertility - Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine - Academic Center for Education, Culture and Research (ACECR) , Fathi ، Rohollah Department of Embryology - Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine - Academic Center for Education, Culture and Research (ACECR) , Valojerdi ، Mojtaba Rezazadeh Department of Embryology - Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine - Academic Center for Education, Culture and Research (ACECR) , Mehdizadeh Kashi ، Abolfazl Endometriosis Research Center - Iran University of Medical Sciences , Khodaverdi ، Sepideh Endometriosis Research Center - Iran University of Medical Sciences , Yahyaei ، Azar Department of Endocrinology and Female Infertility - Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine - Academic Center for Education, Culture and Research (ACECR) , Faridi ، Maziar Department of Surgery - Iranmehr Hospital
Abstract :
Today, timely diagnosis and therapeutic progress open a road of hope for survival in cancerous patients. Increasedknowledge about the various cytotoxic treatment’s impacts on ovarian function and fertility has resulted in a surgein the number of patients seeking to preserve their fertility before starting the anti-cancer treatment process. In thisregard, embryo cryopreservation can be recommended for fertility preservation when the woman is married and hasadequate time for ovarian stimulation. If patients are prepubertal girls or not married women, oocytes or ovarian tissuecan be frozen instead to be used in the future. In this regard, the first attempts for ovarian tissue transplantations wereconducted in 2016 and in 2019 for two cancerous patients whose ovarian tissue was cryopreserved in the RoyanHuman Ovarian Tissue Bank (Tehran, Iran). Unfortunately, the transplantations did not result in a live birth.
Keywords :
fertility preservation , human , Oncofertility , Ovarian tissue , Transplantation