Title of article
Comparative Study of New Biomarkers in Iraqi DM2 with and without Complications
Author/Authors
Salman Jasim ، Husam Department of Chemistry - University of Baghdad , Farooq Altaie ، Anwar Department of Chemistry - University of Baghdad , Touma Saloum ، Warkaa Department of Chemistry - University of Baghdad , Hussein Ali ، Ali Ibn-Albalady Hospital for children and maternity Iraq
From page
400
To page
404
Abstract
Background: Recent research indicates that persistent inflammatory responses may contribute to the rise of diabetic nephropathy (DN) and diabetic cardiovascular disease (DCVD) in type 2 diabetes mellitus patients (DM2). Numerous molecules associated with inflammation and angiogenesis have been implicated in the development and progression of DN and DCVD, respectively. Methods: The subjects were separated into five groups: healthy controls (n= 25), type 2 diabetes mellitus patients (n= 30), type 2 diabetes mellitus patients with nephropathy DN (n= 30), and type 2 diabetes mellitus patients with cardiovascular disease DCVD (n= 30). The blood levels of irisin, IL-8, HbA1C, urea, and creatinine were determined. Results: In current study there was high significant increased irisin levels (p 0.001) in DN patients than other groups and a high significant decreased IL-8 level in DCVD. Conclusions: Serum IL-8 and irisin levels may serve as early indicators of DM2 problems (DN, DCVD).
Keywords
DM2 , DN , DCVD , HbA1C , IL , 8 , Irisin
Journal title
Reports of Biochemistry and Molecular Biology (RBMB)
Journal title
Reports of Biochemistry and Molecular Biology (RBMB)
Record number
2759101
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