Antibacterial Activity of Some Iranian Herbal Essential Oils as Disinfectant Agents on Surfaces Contaminated with Methicillin-resistant-Staphylococcus Aureus and Carbapenem-resistant-Pseudomonas Aeruginosa

Background Objectives: Different essential oils (EOs) with antibacterial activities are promising natural sources for providing novel disinfectant agents for hospital surfaces. Materials Methods: The component and antibacterial effects of six EOs, including Cuminum cyminum (CCEO), Artemisia sieberi (ASEO), Laurus nobilis (LNEO), Ferula gummosa (FGEO), Lippia citriodora (LCEO), and Cymbopogon citratus (CIEO) were assessed by GC-MS and 96-well micro-plates (IC50), against Staphylococcus aureus and Pseudomonas aeruginosa. Then, the antibacterial effects of FGEO, the most effective EO, were evaluated on the trolley surface in a hospital for 1, 3, 5 and 10 min intervals. Results: While CCEO, ASEO, and FGEO have the highest effects on the growth of S. aureus, CIEO and LNEO showed the best outcomes on P. aeruginosa. In addition, our finding showed that FGEO relatively decreases the growth of S. aureus and P. aeruginosa on the trolley surface (P 0.05). Conclusion: The studied EOs could be novel encouraging agents to develop further green antimicrobial agents against different infections. In addition, FGEO, one of the best disinfectant agents in the present study, showed relatively strong antibacterial effects on the surface of the trolley.