Effect of COVID-19 Infection on Kidney Function and Some Related Hormones

Aims: The current study aimed to determine the influence of COVID-19 infection on kidney function and the levels of some related hormones. Instrument Methods: In this experimental study, some severe patients were admitted to the Ibn Al-Khatib Hospital in Baghdad City, Iraq, from May to October 2021, at the end stage of the pandemic. All positive cases (n=60) were entered into the study, and a sample of 31 healthy individuals was also selected as the control group. Urea, uric acid, creatinine, and ADH, EPO were estimated in patients’ serum samples with severe COVID-19. The Independent T-test and Pearson correlation coefficient were used for the analysis. Findings: There were significant differences between the patient and control groups in the total levels of urea (p=0.04), creatinine (p=0.009), uric acid (p=0.009), erythropoietin (p=0.0001), and antidiuretic hormone (p=0.0001) except calcium (p=0.085). Female patients and controls significantly differed in uric acid levels and the other two hormones. Male patients and controls revealed significant differences in Creatinine and both hormones. Calcium and urea represented a significantly higher elevation in male than female patients. Conclusion: Recombinant human erythropoietin weakens distress syndrome of the respiratory system and opposes SARS-COV-2.