Effects of sophoroflavonoside and narcissin flavonoids on the amount of malondialdehyde, a product of lipid peroxidation, and the activity of the enzyme cytochrome c oxidase in rat liver mitochondria poisoned with indoxacarb pesticide

In this study, the effects of soforaflavonolonoside and narcissin flavonoids on the amount of malondialdehyde, a product of peroxidation of lipids in the liver mitochondria of rats poisoned with indoxacarb pesticide, and on the activity of the enzyme cytochrome-s-oxidase were studied depending on the dynamics of 10, 20, 30 and 40 days. The experimental group was injected with indoxacarb pesticide at a dose of 1/10 LD50 through a special probe. After administration of indoxacarb pesticide, animals were administered orally with soforaflavonolonoside and narcissin flavonoid at a dose of 10 mg kg-1 once a day for 10 days.