Title of article
Regulation of cell fate by cell imprinting approach in vitro
Author/Authors
Hasannejad ، Farkhonde Department of Tissue Engineering and Applied Cell Sciences - School of Medicine - Semnan University of Medical Science , Montazeri ، Leila Department of Cell Engineering - Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology - Academic Center for Education, Culture and Research (ACECR) , Mano ، João F Department of Chemistry - CICECO - Aveiro Institute of Materials - University of Aveiro , Bonakdar ، Shahin National Cell Bank Department - Pasteur Institute of Iran , Fazilat ، Ahmad Genetic Department - Breast Cancer Research Center, Motamed Cancer Institute - Academic Center for Education, Culture and Research (ACECR)
From page
1
To page
23
Abstract
Cell culture-based technologies are widely utilized in various domains such as drug evaluation, toxicity assessment, vaccine and biopharmaceutical development, reproductive technology, and regenerative medicine. It has been demonstrated that pre-adsorption of extracellular matrix (ECM) proteins including collagen, laminin and fibronectin provide more degrees of support for cell adhesion. The purpose of cell imprinting is to imitate the natural topography of cell membranes by gels or polymers to create a reliable environment for the regulation of cell function. The results of recent studies show that cell imprinting is a tool to guide the behavior of cultured cells by controlling their adhesive interactions with surfaces. Therefore, in this review we aim to compare different cell cultures with the imprinting method and discuss different cell imprinting applications in regenerative medicine, personalized medicine, disease modeling, and cell therapy.
Keywords
Cell imprinting , Molecular imprinting , Disease modeling , Personalized medicine , Cell therapy , Regenerative medicine
Journal title
Bioimpacts
Journal title
Bioimpacts
Record number
2766895
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