Title of article
Effects of K5SiW11O39Co on Mitogenic Activity of Basic Fibroblast Growth Factor
Author/Authors
Sun، Liwei نويسنده , , Wu، Qiang نويسنده , , Liu، Ning نويسنده , , Yang، Cheng نويسنده , , Liu، Liyan نويسنده , , Liu، Zhiqiang نويسنده , , Zhao، Daqing نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
-297
From page
298
To page
0
Abstract
The interaction between polyoxometalate (POM) of Keggin class (K5SiW11O39Co) and human basic fibroblast growth factor (bFGF) was studied by fluorescence and CD spectra. The results indicate that the binding of POM to bFGF causes conformational changes of bFGF. The cell proliferation assay showed that in lower molar ratios, POM stimulates mitogenic activity of bFGF; in higher molar ratios, POM inhibits the mitogenic activity of bFGF.
Keywords
Power requirement , Application-production research , Genetic-fuzzy system , prediction , Surface finish , grinding
Journal title
CHEMISTRY LETTERS
Serial Year
2004
Journal title
CHEMISTRY LETTERS
Record number
27677
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