Title of article
An Effectual Eco-Friendly Protocol for the Construction of 4,6-Diarylpyrimidin-2(1H)-Ones
Author/Authors
Zare ، Abdolkarim Department of Chemistry - Faculty of Nano and Bio Science and Technology - Persian Gulf University , Khanivar ، Roghayyeh Department of Chemistry - Payame Noor University
From page
539
To page
548
Abstract
An effectual eco-friendly protocol for the construction of 4,6-diarylpyrimidin-2(1H)-ones has been described through a solvent-free one-pot multi-component reaction. The condensation of urea, aryl aldehydes, and acetophenones in the Me3SiCl presence produced 4,6-diarylpyrimidin-2(1H)-ones in high yields and relatively short times. In the reported protocols, a catalyst has been used beside Me3SiCl. However, in our protocol, there was no need to utilize a catalyst.
Keywords
Aryl aldehyde , Acetophenones , Urea , 4 , 6 , Diarylpyrimidin , 2(1H) , one , Solvent , free , Multi , component reaction
Journal title
Asian Journal of Green Chemistry
Journal title
Asian Journal of Green Chemistry
Record number
2767733
Link To Document